The LE220 Focused-ultrasonicator is a versatile system engineered for high throughput pre-analytical sample processing by Adaptive Focused Acoustics™. The LE220 utilizes a unique line-shaped transducer and computer controlled electronics to deliver highly controlled acoustic energy to the focal zone. The LE220 Focused-ultrasonicator delivers the same reproducibility as the renowned S-Series and E-Series AFA Instruments, so you can be assured that tube-to-tube and row-to-row precision is excellent.
The LE220 is specifically designed for operations requiring a higher throughput Covaris AFA solution. With highly reproducible performance characteristics matching Covaris S-Series and E-Series instruments, the LE220 applies controlled acoustic energy to multiple samples at one time. For example, in a 96 microTUBE Plate, a row of 8 samples is treated simultaneously by the LE220’s line transducer. By indexing all 12 rows across the acoustic field, 96 samples are processed 8X faster than with a single-sample instrument. The LE220 capably manages a wide variety of sample formats in an SBS microplate footprint (including 8, 24, 48, 96), processing an entire row at a time.
Key applications for the LE220 include: DNA shearing for Next-Gen sequencing, cell lysis, tissue disruption, and compound dissolution.
Focused-ultrasonicators with AFA Technology operate at frequencies well beyond the range of human hearing (500KHz) so, unlike traditional laboratory sonicators, they are inaudible and do not require sound-proof boxes or other special precautions.
The LE220 is also available in the robotic capable (LE220R) configuration.