LE220-plus Focused-ultrasonicator

Standardize your workflow in NGS, proteomics, or compound management

LE220-plus Flyer

DNA Shearing Quick Guide

Key Features

  • Accurate, reproducible, and robust sample preparation powered by (AFA®) Adaptive Focused Acoustics® technology
  • Designed for integration with high throughput laboratory automation with no water adjustment necessary
  • User-defined scheduling for system set-up maximizes laboratory efficiency

Complete Walk-away Solution with the LE220-plus

Set-up, Scheduled, and Ready to Go

The LE220-plus incorporates automatic water level detection and automatic z-height adjustment maintaining the AFA acoustic vessels at a constant, optimal distance from the ultrasonic transducer. These features control the LE220-plus to ensure reproducible AFA performance for any operator while providing hands free operation.

 

User-friendly Software – SonoLab 8.1

System Ready –> Method Loaded –> Run

 

 

The LE220-plus system includes control connections to both the AFA ultraCUBE water chiller and the water conditioning module. Significant improvements to laboratory efficiency are enabled with our latest SonoLab software which features a simple, intuitive interface along with a module for remote start-up and daily scheduling.

⇐ Watch this video for a SonoLab demo

 

Product Specifications
Consumables

The LE220-plus system is compatible with existing LE220 protocols and consumables. In addition, the LE220-plus is available as an upgrade to an L- or E-Series or as stand-alone purchase.

Part Number 500569
Treatment Power 2.5 to 500 Watts Peak Incident Power 0.1 to 250 Watts Average Incident Power
Dimensions 61 cm (width) x 76 cm (depth) x 48 cm (height)
Power Requirements 100-240 VAC 500 VA, 50-60Hz
Operating Environment Ambient temperature: 19° C to 25° C (66° F to 77° C) Relative humidity: 30% to 70%
Regulatory Labeling CE, ETL Mark (for Product Safety), WEEE
Safety Complies with Low Voltage Directive 2006/95/EC. Certified to IEC/EN/ANSI/UL 61010-1:2010 and CAN/CSA C22.2 No. 61010-1, “Safety Requirements for Electrical Equipment for Measurement, Control and Laboratory Use, Part 1: General Requirements”
EMC Complies with Class A Industrial/Scientific/Medical (ISM) equipment under EN 61326-1 for EU EMC Directive 2014/30/EU. Also FCC Part 15 Class A radio emissions requirements for the USA and ICES-003 Class A for Industry CanadaComplies with Class A Industrial/Scientific/Medical (ISM) equipment under EN 61326-1 for EU EMC Directive 2014/30/EU. Also FCC Part 15 Class A radio emissions requirements for the USA and ICES-003 Class A for Industry Canada
Operating System Includes: Notebook computer interface via USB with Microsoft Windows and Covaris SonoLab™ Operating
Software installed
Chiller ThermoCube and WCS 2.0 required
Sample Processing Capacity 1 to 8 tubes at a time parallel processing; 96 tube capacity
NGS Sample Volume 5 to 500 μL
Sample Volumes truXTRAC FFPE = LCM, 5 to 20 micron slides, up to 80 micron slices, and 1.2 mm cores
truXTRAC cfDNA = up to 4 ml plasma
truXTRAC DBS (dried blood spots) = up to seven 3 mm punches
truCHIP (chromatin) = up to 1 mL for mammalian cells
truCOLLECT = up to 35 μL fresh whole blood
Recommended Batch Size 96+ samples
Upgrade Potential Robotics upgrade capable
Operator Skill Requirement Minimal
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
Part Number
500569
Treatment Power
2.5 to 500 Watts Peak Incident Power 0.1 to 250 Watts Average Incident Power
Dimensions
61 cm (width) x 76 cm (depth) x 48 cm (height)
Power Requirements
100-240 VAC 500 VA, 50-60Hz
Operating Environment
Ambient temperature: 19° C to 25° C (66° F to 77° C) Relative humidity: 30% to 70%
Regulatory Labeling
CE, ETL Mark (for Product Safety), WEEE
Safety
Complies with Low Voltage Directive 2006/95/EC. Certified to IEC/EN/ANSI/UL 61010-1:2010 and CAN/CSA C22.2 No. 61010-1, “Safety Requirements for Electrical Equipment for Measurement, Control and Laboratory Use, Part 1: General Requirements”
EMC
Complies with Class A Industrial/Scientific/Medical (ISM) equipment under EN 61326-1 for EU EMC Directive 2014/30/EU. Also FCC Part 15 Class A radio emissions requirements for the USA and ICES-003 Class A for Industry CanadaComplies with Class A Industrial/Scientific/Medical (ISM) equipment under EN 61326-1 for EU EMC Directive 2014/30/EU. Also FCC Part 15 Class A radio emissions requirements for the USA and ICES-003 Class A for Industry Canada
Operating System
Includes: Notebook computer interface via USB with Microsoft Windows and Covaris SonoLab™ Operating
Software installed
Chiller
ThermoCube and WCS 2.0 required
Sample Processing Capacity
1 to 8 tubes at a time parallel processing; 96 tube capacity
NGS Sample Volume
5 to 500 μL
Sample Volumes
truXTRAC FFPE = LCM, 5 to 20 micron slides, up to 80 micron slices, and 1.2 mm cores
truXTRAC cfDNA = up to 4 ml plasma
truXTRAC DBS (dried blood spots) = up to seven 3 mm punches
truCHIP (chromatin) = up to 1 mL for mammalian cells
truCOLLECT = up to 35 μL fresh whole blood
Recommended Batch Size
96+ samples
Upgrade Potential
Robotics upgrade capable
Operator Skill Requirement
Minimal