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Posttranscriptional Regulation of 14q32 MicroRNAs by the CIRBP and HADHB during Vascular Regeneration after Ischemia.
Downie Ruiz Velasco A, Welten SMJ, Goossens EAC, Quax PHA, Rappsilber J, Michlewski G, Nossent AY.
Molecular therapy. Nucleic acids. 2018 Dec 6;14:329-338 | doi: 10.1016/j.omtn.2018.11.017 | PMID: 30665182
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Development of a gene-editing approach to restore vision loss in Leber congenital amaurosis type 10.
Maeder ML, Stefanidakis M, Wilson CJ, Baral R, Barrera LA, Bounoutas GS, Bumcrot D, Chao H, Ciulla DM, DaSilva JA, Dass A, Dhanapal V, Fennell TJ, Friedland AE, Giannoukos G, Gloskowski SW, Glucksmann A, Gotta GM, Jayaram H, Haskett SJ, Hopkins B, Horng JE, Joshi S, Marco E, Mepani R, Reyon D, Ta T, Tabbaa DG, Samuelsson SJ, Shen S, Skor MN, Stetkiewicz P, Wang T, Yudkoff C, Myer VE, Albright CF, Jiang H.
Nature medicine. 2019 Jan 21; | doi: 10.1038/s41591-018-0327-9 | PMID: 30664785
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Small-molecule targeting of brachyury transcription factor addiction in chordoma.
Sharifnia T, Wawer MJ, Chen T, Huang QY, Weir BA, Sizemore A, Lawlor MA, Goodale A, Cowley GS, Vazquez F, Ott CJ, Francis JM, Sassi S, Cogswell P, Sheppard HE, Zhang T, Gray NS, Clarke PA, Blagg J, Workman P, Sommer J, Hornicek F, Root DE, Hahn WC, Bradner JE, Wong KK, Clemons PA, Lin CY, Kotz JD, Schreiber SL.
Nature medicine. 2019 Jan 21; | doi: 10.1038/s41591-018-0312-3 | PMID: 30664779
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Structural insights into a high fidelity variant of SpCas9.
Guo M, Ren K, Zhu Y, Tang Z, Wang Y, Zhang B, Huang Z.
Cell research. 2019 Jan 21; | doi: 10.1038/s41422-018-0131-6 | PMID: 30664728
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CRISPR-Cas: a tool for cancer research and therapeutics.
Yin H, Xue W, Anderson DG.
Nature reviews. Clinical oncology. 2019 Jan 21; | doi: 10.1038/s41571-019-0166-8 | PMID: 30664678
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BAP1 complex promotes transcription by opposing PRC1-mediated H2A ubiquitylation.
Campagne A, Lee MK, Zielinski D, Michaud A, Le Corre S, Dingli F, Chen H, Shahidian LZ, Vassilev I, Servant N, Loew D, Pasmant E, Postel-Vinay S, Wassef M, Margueron R.
Nature communications. 2019 Jan 21;10(1):348 | doi: 10.1038/s41467-018-08255-x | PMID: 30664650
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An undergraduate laboratory experience using CRISPR-Cas9 technology to deactivate green fluorescent protein expression in Escherichia coli.
Pieczynski JN, Deets A, McDuffee A, Lynn Kee H.
Biochemistry and molecular biology education : a bimonthly publication of the International Union of Biochemistry and Molecular Biology. 2019 Jan 21; | doi: 10.1002/bmb.21206 | PMID: 30664332
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Nodule-specific PLAT domain proteins are expanded in the Medicago lineage and required for nodulation.
Trujillo DI, Silverstein KAT, Young ND.
The New phytologist. 2019 Jan 21; | doi: 10.1111/nph.15697 | PMID: 30664233
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Investigation of Genetic Dependencies Using CRISPR-Cas9-based Competition Assays.
Deshpande A, Chen BR, Zhao L, Saddoris K, Kerr M, Zhu N, Mali P, Deshpande AJ.
Journal of visualized experiments : JoVE. 2019 Jan 7;(143) | doi: 10.3791/58710 | PMID: 30663717
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Generating Recombinant Avian Herpesvirus Vectors with CRISPR/Cas9 Gene Editing.
Tang N, Zhang Y, Pedrera M, Chang P, Baigent S, Moffat K, Shen Z, Nair V, Yao Y.
Journal of visualized experiments : JoVE. 2019 Jan 7;(143) | doi: 10.3791/58193 | PMID: 30663658
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Plasmid Curing Resulted in Improved Heterologous Gene Expression in Leuconostoc citreum EFEL2700.
Jang YJ, Kim SA, Seo SO, Li L, Han NS.
Letters in applied microbiology. 2019 Jan 21; | doi: 10.1111/lam.13118 | PMID: 30663071
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Differential ACPA Binding to Nuclear Antigens Reveals a PAD-Independent Pathway and a Distinct Subset of Acetylation Cross-Reactive Autoantibodies in Rheumatoid Arthritis.
Lloyd KA, Wigerblad G, Sahlström P, Garimella MG, Chemin K, Steen J, Titcombe PJ, Marklein B, Zhou D, Stålesen R, Ossipova E, Lundqvist C, Ekwall O, Rönnelid J, Mueller DL, Karlsson MCI, Kaplan MJ, Skriner K, Klareskog L, Wermeling F, Malmström V, Grönwall C.
Frontiers in immunology. 2018;9:3033 | doi: 10.3389/fimmu.2018.03033 | PMID: 30662440 | PMC: PMC6328449
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CRISPR/Cas9-Mediated Chicken TBK1 Gene Knockout and Its Essential Role in STING-Mediated IFN-β Induction in Chicken Cells.
Cheng Y, Lun M, Liu Y, Wang H, Yan Y, Sun J.
Frontiers in immunology. 2018;9:3010 | doi: 10.3389/fimmu.2018.03010 | PMID: 30662438 | PMC: PMC6328437
Tóm tắt Chức năng
Glycerol kinase 2 is essential for proper arrangement of crescent-like mitochondria to form the mitochondrial sheath during mouse spermatogenesis.
Shimada K, Kato H, Miyata H, Ikawa M.
The Journal of reproduction and development. 2019 Jan 21; | doi: 10.1262/jrd.2018-136 | PMID: 30662012
Tóm tắt Chức năng
Imprecise Spacer Acquisition Generates CRISPR-Cas Immune Diversity through Primed Adaptation.
Jackson SA, Birkholz N, Malone LM, Fineran PC.
Cell host & microbe. 2019 Jan 8; | doi: 10.1016/j.chom.2018.12.014 | PMID: 30661951
Tóm tắt Chức năng
Environmental Control of Astrocyte Pathogenic Activities in CNS Inflammation.
Wheeler MA, Jaronen M, Covacu R, Zandee SEJ, Scalisi G, Rothhammer V, Tjon EC, Chao CC, Kenison JE, Blain M, Rao VTS, Hewson P, Barroso A, Gutiérrez-Vázquez C, Prat A, Antel JP, Hauser R, Quintana FJ.
Cell. 2019 Jan 14; | doi: 10.1016/j.cell.2018.12.012 | PMID: 30661753
Tóm tắt Chức năng
Redundancy of human ATG4 protease isoforms in autophagy and LC3/GABARAP processing revealed in cells.
Agrotis A, Pengo N, Burden JJ, Ketteler R.
Autophagy. 2019 Jan 21; | doi: 10.1080/15548627.2019.1569925 | PMID: 30661429
Tóm tắt Chức năng
A CRISPR Screen Identifies LAPTM4A and TM9SF Proteins as Glycolipid-Regulating Factors.
Yamaji T, Sekizuka T, Tachida Y, Sakuma C, Morimoto K, Kuroda M, Hanada K.
iScience. 2019 Jan 3;11:409-424 | doi: 10.1016/j.isci.2018.12.039 | PMID: 30660999
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Generation of a set of isogenic, gene-edited iPSC lines homozygous for all main APOE variants and an APOE knock-out line.
Schmid B, Prehn KR, Nimsanor N, Garcia BIA, Poulsen U, Jørring I, Rasmussen MA, Clausen C, Mau-Holzmann UA, Ramakrishna S, Muddashetty R, Steeg R, Bruce K, Mackintosh P, Ebneth A, Holst B, Cabrera-Socorro A.
Stem cell research. 2019 Jan 4;34:101349 | doi: 10.1016/j.scr.2018.11.010 | PMID: 30660866
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Aberrant enhancer hypomethylation contributes to hepatic carcinogenesis through global transcriptional reprogramming.
Xiong L, Wu F, Wu Q, Xu L, Cheung OK, Kang W, Mok MT, Szeto LLM, Lun CY, Lung RW, Zhang J, Yu KH, Lee SD, Huang G, Wang CM, Liu J, Yu Z, Yu DY, Chou JL, Huang WH, Feng B, Cheung YS, Lai PB, Tan P, Wong N, Chan MW, Huang TH, Yip KY, Cheng AS, To KF.
Nature communications. 2019 Jan 18;10(1):335 | doi: 10.1038/s41467-018-08245-z | PMID: 30659195
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A complex between phosphatidylinositol 4 kinase IIα and integrin α3β1 is required for N-glycan sialylation in cancer cells.
Isaji T, Im S, Kameyama A, Wang Y, Fukuda T, Gu J.
The Journal of biological chemistry. 2019 Jan 18; | doi: 10.1074/jbc.RA118.005208 | PMID: 30659093
Tóm tắt Chức năng
Blockade of a laminin-411 - Notch axis with CRISPR/Cas9 or a nanobioconjugate inhibits glioblastoma growth through tumor-microenvironment crosstalk.
Sun T, Patil R, Galstyan A, Klymyshyn D, Ding H, Chesnokova A, Cavenee WK, Furnari FB, Ljubimov VA, Shatalova ES, Wagner S, Li D, Mamelak AN, Bannykh SI, Patil CG, Rudnick JD, Hu J, Grodzinski ZB, Rekechenetskiy A, Falahatian V, Lyubimov AV, Chen YL, Leoh LS, Daniels-Wells TR, Penichet ML, Holler E, Ljubimov AV, Black KL, Ljubimova JY.
Cancer research. 2019 Jan 18; | doi: 10.1158/0008-5472.CAN-18-2725 | PMID: 30659021
Tóm tắt Chức năng
Generation of NERCe003-A-3, a p53 compound heterozygous mutation human embryonic stem cell line, by CRISPR/Cas9 editing.
Li Y, Huang C, Zha L, Kong M, Yang Q, Zhu Y, Peng Y, Ouyang Q, Lu G, Lin G, Zhou D.
Stem cell research. 2018 Dec 17;34:101371 | doi: 10.1016/j.scr.2018.101371 | PMID: 30658254
Tóm tắt Chức năng
Differential use of E2 ubiquitin conjugating enzymes for regulated degradation of the rate-limiting enzymes HMGCR and SQLE in cholesterol biosynthesis.
Tan JME, Cook ECL, van den Berg M, Scheij S, Zelcer N, Loregger A.
Atherosclerosis. 2018 Dec 23;281:137-142 | doi: 10.1016/j.atherosclerosis.2018.12.008 | PMID: 30658189
Tóm tắt Chức năng
N-Myc promotes therapeutic resistance development of neuroendocrine prostate cancer by differentially regulating miR-421/ATM pathway.
Yin Y, Xu L, Chang Y, Zeng T, Chen X, Wang A, Groth J, Foo WC, Liang C, Hu H, Huang J.
Molecular cancer. 2019 Jan 18;18(1):11 | doi: 10.1186/s12943-019-0941-2 | PMID: 30657058
Tóm tắt Chức năng
Nicastrin haploinsufficiency alters expression of type I interferon-stimulated genes: the relationship to familial hidradenitis suppurativa.
Cao L, Morales-Heil DJ, Roberson EDO.
Clinical and experimental dermatology. 2019 Jan 17; | doi: 10.1111/ced.13906 | PMID: 30656721
Tóm tắt Chức năng
Generating Neural Stem Cells from iPSCs with Dopaminergic Neurons Reporter Gene.
Hong H, Daadi MM.
Methods in molecular biology (Clifton, N.J.). 2019;1919:119-128 | doi: 10.1007/978-1-4939-9007-8_9 | PMID: 30656625
Tóm tắt Chức năng
Engineering of lactic acid bacteria for delivery of therapeutic proteins and peptides.
Plavec TV, Berlec A.
Applied microbiology and biotechnology. 2019 Jan 17; | doi: 10.1007/s00253-019-09628-y | PMID: 30656391
Tóm tắt Chức năng
Effects of the Prdx2 depletion on blood pressure and life span in spontaneously hypertensive rats.
Mahal Z, Fujikawa K, Matsuo H, Zahid HM, Koike M, Misumi M, Kaneko T, Mashimo T, Ohara H, Nabika T.
Hypertension research : official journal of the Japanese Society of Hypertension. 2019 Jan 17; | doi: 10.1038/s41440-019-0207-9 | PMID: 30655626
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CRISPR/Cas9-mediated one step bi-allelic change of genomic DNA in iPSCs and human RPE cells in vitro with dual antibiotic selection.
Supharattanasitthi W, Carlsson E, Sharif U, Paraoan L.
Scientific reports. 2019 Jan 17;9(1):174 | doi: 10.1038/s41598-018-36740-2 | PMID: 30655567
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A genome-wide CRISPR screen identifies N-acetylglucosamine-1-phosphate transferase as a potential antiviral target for Ebola virus.
Flint M, Chatterjee P, Lin DL, McMullan LK, Shrivastava-Ranjan P, Bergeron É, Lo MK, Welch SR, Nichol ST, Tai AW, Spiropoulou CF.
Nature communications. 2019 Jan 17;10(1):285 | doi: 10.1038/s41467-018-08135-4 | PMID: 30655525
Tóm tắt Chức năng
CRISPR analysis suggests that small circular single-stranded DNA smacoviruses infect Archaea instead of humans.
Díez-Villaseñor C, Rodriguez-Valera F.
Nature communications. 2019 Jan 17;10(1):294 | doi: 10.1038/s41467-018-08167-w | PMID: 30655519
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The RUNX transcriptional co-regulator, CBFβ, suppresses migration of ER+ breast cancer cells by repressing ERα-mediated expression of the migratory factor TFF1.
Pegg HJ, Harrison H, Rogerson C, Shore P.
Molecular cancer research : MCR. 2019 Jan 17; | doi: 10.1158/1541-7786.MCR-18-1039 | PMID: 30655324
Tóm tắt Chức năng
CRISPR/Cas Systems towards Next-Generation Biosensing.
Li Y, Li S, Wang J, Liu G.
Trends in biotechnology. 2019 Jan 14; | doi: 10.1016/j.tibtech.2018.12.005 | PMID: 30654914
Tóm tắt Chức năng
iGUIDE: an improved pipeline for analyzing CRISPR cleavage specificity.
Nobles CL, Reddy S, Salas-McKee J, Liu X, June CH, Melenhorst JJ, Davis MM, Zhao Y, Bushman FD.
Genome biology. 2019 Jan 17;20(1):14 | doi: 10.1186/s13059-019-1625-3 | PMID: 30654827
Tóm tắt Chức năng
Activating PTEN Tumor Suppressor Expression with the CRISPR/dCas9 System.
Moses C, Nugent F, Waryah CB, Garcia-Bloj B, Harvey AR, Blancafort P.
Molecular therapy. Nucleic acids. 2018 Dec 14;14:287-300 | doi: 10.1016/j.omtn.2018.12.003 | PMID: 30654190
Tóm tắt Chức năng
Enhancing responsiveness of pancreatic cancer cells to gemcitabine treatment under hypoxia by heme oxygenase-1 inhibition.
Abdalla MY, Ahmad IM, Rachagani S, Banerjee K, Thompson CM, Maurer HC, Olive KP, Bailey KL, Britigan BE, Kumar S.
Translational research : the journal of laboratory and clinical medicine. 2019 Jan 4; | doi: 10.1016/j.trsl.2018.12.008 | PMID: 30653942
Tóm tắt Chức năng
A new approach to Cas9-based genome editing in Aspergillus niger that is precise, efficient and selectable.
Leynaud-Kieffer LMC, Curran SC, Kim I, Magnuson JK, Gladden JM, Baker SE, Simmons BA.
PloS one. 2019;14(1):e0210243 | doi: 10.1371/journal.pone.0210243 | PMID: 30653574
Tóm tắt Chức năng
[Gene editing].
Węgleński P.
Postepy biochemii. 2018 Jun 30;64(1):9-12 | PMID: 30652832
Tóm tắt Chức năng
Critical function of DNA methyltransferase 1 in tomato development and regulation of the DNA methylome and transcriptome.
Yang Y, Tang K, Datsenka TU, Liu W, Lv S, Lang Z, Wang X, Gao J, Wang W, Nie W, Chu Z, Zhang H, Handa AK, Zhu JK, Zhang H.
Journal of integrative plant biology. 2019 Jan 16; | doi: 10.1111/jipb.12778 | PMID: 30652405
Tóm tắt Chức năng
Genome Editing by CRISPR/Cas9 in Sorghum Through Biolistic Bombardment.
Liu G, Li J, Godwin ID.
Methods in molecular biology (Clifton, N.J.). 2019;1931:169-183 | doi: 10.1007/978-1-4939-9039-9_12 | PMID: 30652290
Tóm tắt Chức năng
Gene Editing in Sorghum Through Agrobacterium.
Sander JD.
Methods in molecular biology (Clifton, N.J.). 2019;1931:155-168 | doi: 10.1007/978-1-4939-9039-9_11 | PMID: 30652289
Tóm tắt Chức năng
Reduction of Kaposi's sarcoma-associated herpesvirus latency using CRISPR-Cas9 to edit the latency-associated nuclear antigen gene.
Tso FY, West JT, Wood C.
Journal of virology. 2019 Jan 16; | doi: 10.1128/JVI.02183-18 | PMID: 30651362
Tóm tắt Chức năng
Human iPSC-Chimera Xenotransplantation and the Non-Identity Problem.
Casal P, Williams A.
Journal of clinical medicine. 2019 Jan 15;8(1) | doi: 10.3390/jcm8010095 | PMID: 30650626
Tóm tắt Chức năng
Dystrophin Deficiency Leads to Genomic Instability in Human Pluripotent Stem Cells via NO Synthase-Induced Oxidative Stress.
Jelinkova S, Fojtik P, Kohutova A, Vilotic A, Marková L, Pesl M, Jurakova T, Kruta M, Vrbsky J, Gaillyova R, Valášková I, Frák I, Lacampagne A, Forte G, Dvorak P, Meli AC, Rotrekl V.
Cells. 2019 Jan 15;8(1) | doi: 10.3390/cells8010053 | PMID: 30650618
Tóm tắt Chức năng
Efficient and transgene-free gene targeting using Agrobacterium-mediated delivery of the CRISPR/Cas9 system in tomato.
Danilo B, Perrot L, Mara K, Botton E, Nogué F, Mazier M.
Plant cell reports. 2019 Jan 16; | doi: 10.1007/s00299-019-02373-6 | PMID: 30649572
Tóm tắt Chức năng
Structural insights reveal the specific recognition of roX RNA by the dsRNA-binding domains of the RNA helicase MLE and its indispensable role in dosage compensation in Drosophila.
Lv M, Yao Y, Li F, Xu L, Yang L, Gong Q, Xu YZ, Shi Y, Fan YJ, Tang Y.
Nucleic acids research. 2019 Jan 15; | doi: 10.1093/nar/gky1308 | PMID: 30649456
Tóm tắt Chức năng
Crisflash: Open-source software to generate CRISPR guide RNAs against genomes annotated with individual variation.
Jacquin AL, Odom DT, Lukk M.
Bioinformatics (Oxford, England). 2019 Jan 12; | doi: 10.1093/bioinformatics/btz019 | PMID: 30649181
Tóm tắt Chức năng
Reprogramming the antigen specificity of B cells using genome-editing technologies.
Voss JE, Gonzalez-Martin A, Andrabi R, Fuller RP, Murrell B, McCoy LE, Porter K, Huang D, Li W, Sok D, Le K, Briney B, Chateau M, Rogers G, Hangartner L, Feeney AJ, Nemazee D, Cannon P, Burton D.
eLife. 2019 Jan 16;8 | doi: 10.7554/eLife.42995 | PMID: 30648968
Tóm tắt Chức năng
Questions answered and unanswered by the first CRISPR editing study in the canine model of Duchenne muscular dystrophy.
Wasala NB, Hakim C, Chen SJ, Yang NN, Duan D.
Human gene therapy. 2019 Jan 16; | doi: 10.1089/hum.2018.243 | PMID: 30648435
Tóm tắt Chức năng
Detection and variability analyses of CRISPR-like loci in the H. pylori genome.
García-Zea JA, de la Herrán R, Robles Rodríguez F, Navajas-Pérez R, Ruiz Rejón C.
PeerJ. 2019;7:e6221 | doi: 10.7717/peerj.6221 | PMID: 30648020 | PMC: PMC6330956
Tóm tắt Chức năng
A review on advanced methods in plant gene targeting.
Sanagala R, Moola AK, Bollipo Diana RK.
Journal, genetic engineering & biotechnology. 2017 Dec;15(2):317-321 | doi: 10.1016/j.jgeb.2017.07.004 | PMID: 30647669 | PMC: PMC6296621
Tóm tắt Chức năng
CRISPR adapted to respond to infected cells.
Nature. 2019 Jan;565(7739):268-269 | doi: 10.1038/d41586-019-00129-6 | PMID: 30647425
Tóm tắt Chức năng
Erratum for Penewit et al., "Efficient and Scalable Precision Genome Editing in Staphylococcus aureus through Conditional Recombineering and CRISPR/Cas9-Mediated Counterselection".
Penewit K, Holmes EA, McLean K, Ren M, Waalkes A, Salipante SJ.
mBio. 2019 Jan 15;10(1) | doi: 10.1128/mBio.02698-18 | PMID: 30647160
Tóm tắt Chức năng
Bile acid analogues are activators of Pyrin inflammasome.
Alimov I, Menon S, Cochran N, Maher R, Wang Q, Alford J, Concannon JB, Yang Z, Harrington E, Llamas L, Lindeman A, Hoffman G, Schuhmann T, Russ C, Reece-Hoyes J, Canham SM, Cai X.
The Journal of biological chemistry. 2019 Jan 15; | doi: 10.1074/jbc.RA118.005103 | PMID: 30647128
Tóm tắt Chức năng
In vivo genome and base editing of a human PCSK9 knock-in hypercholesterolemic mouse model.
Carreras A, Pane LS, Nitsch R, Madeyski-Bengtson K, Porritt M, Akcakaya P, Taheri-Ghahfarokhi A, Ericson E, Bjursell M, Perez-Alcazar M, Seeliger F, Althage M, Knöll R, Hicks R, Mayr LM, Perkins R, Lindén D, Borén J, Bohlooly-Y M, Maresca M.
BMC biology. 2019 Jan 15;17(1):4 | doi: 10.1186/s12915-018-0624-2 | PMID: 30646909
Tóm tắt Chức năng
Homologous recombination-mediated targeted integration in monkey embryos using TALE nucleases.
Chu C, Yang Z, Yang J, Yan L, Si C, Kang Y, Chen Z, Chen Y, Ji W, Niu Y.
BMC biotechnology. 2019 Jan 15;19(1):7 | doi: 10.1186/s12896-018-0494-2 | PMID: 30646876
Tóm tắt Chức năng
The CRISPR/Cas9 system and its applications in crop genome editing.
Bao A, Burritt DJ, Chen H, Zhou X, Cao D, Tran LP.
Critical reviews in biotechnology. 2019 Jan 15;:1-16 | doi: 10.1080/07388551.2018.1554621 | PMID: 30646772
Tóm tắt Chức năng
CRISPR/Cas9-mediated targeted T-DNA integration in rice.
Lee K, Eggenberger AL, Banakar R, McCaw ME, Zhu H, Main M, Kang M, Gelvin SB, Wang K.
Plant molecular biology. 2019 Jan 15; | doi: 10.1007/s11103-018-00819-1 | PMID: 30645710
Tóm tắt Chức năng
Reiterative Enrichment and Authentication of CRISPRi Targets (REACT) identifies the proteasome as a key contributor to HIV-1 latency.
Li Z, Wu J, Chavez L, Hoh R, Deeks SG, Pillai SK, Zhou Q.
PLoS pathogens. 2019 Jan;15(1):e1007498 | doi: 10.1371/journal.ppat.1007498 | PMID: 30645648
Tóm tắt Chức năng
CRISPR-Cas9 interrogation of a putative fetal globin repressor in human erythroid cells.
Chung JE, Magis W, Vu J, Heo SJ, Wartiovaara K, Walters MC, Kurita R, Nakamura Y, Boffelli D, Martin DIK, Corn JE, DeWitt MA.
PloS one. 2019;14(1):e0208237 | doi: 10.1371/journal.pone.0208237 | PMID: 30645582
Tóm tắt Chức năng
Programmed genome editing of the omega-1 ribonuclease of the blood fluke, Schistosoma mansoni.
Ittiprasert W, Mann VH, Karinshak SE, Coghlan A, Rinaldi G, Sankaranarayanan G, Chaidee A, Tanno T, KumKhaek C, Prangtaworn P, Mentink-Kane MM, Cochran CJ, Driguez P, Holroyd N, Tracey A, Rodpai R, Everts B, Hokke CH, Hoffmann KF, Berriman M, Brindley PJ.
eLife. 2019 Jan 15;8 | doi: 10.7554/eLife.41337 | PMID: 30644357
Tóm tắt Chức năng
Oligonucleotide Therapeutics as a New Class of Drugs for Malignant Brain Tumors: Targeting mRNAs, Regulatory RNAs, Mutations, Combinations, and Beyond.
Krichevsky AM, Uhlmann EJ.
Neurotherapeutics : the journal of the American Society for Experimental NeuroTherapeutics. 2019 Jan 14; | doi: 10.1007/s13311-018-00702-3 | PMID: 30644073
Tóm tắt Chức năng
CRISPR/Cas9-Mediated Multiply Targeted Mutagenesis in Orange and Purple Carrot Plants.
Xu ZS, Feng K, Xiong AS.
Molecular biotechnology. 2019 Jan 14; | doi: 10.1007/s12033-018-00150-6 | PMID: 30644027
Tóm tắt Chức năng
Multistage Delivery Nanoparticle Facilitates Efficient CRISPR/dCas9 Activation and Tumor Growth Suppression In Vivo.
Liu Q, Zhao K, Wang C, Zhang Z, Zheng C, Zhao Y, Zheng Y, Liu C, An Y, Shi L, Kang C, Liu Y.
Advanced science (Weinheim, Baden-Wurttemberg, Germany). 2019 Jan 9;6(1):1801423 | doi: 10.1002/advs.201801423 | PMID: 30643726 | PMC: PMC6325604
Tóm tắt Chức năng
hdac4 mediates perichondral ossification and pharyngeal skeleton development in the zebrafish.
DeLaurier A, Alvarez CL, Wiggins KJ.
PeerJ. 2019;7:e6167 | doi: 10.7717/peerj.6167 | PMID: 30643696 | PMC: PMC6329341
Tóm tắt Chức năng
IFITM3 directly engages and shuttles incoming virus particles to lysosomes.
Spence JS, He R, Hoffmann HH, Das T, Thinon E, Rice CM, Peng T, Chandran K, Hang HC.
Nature chemical biology. 2019 Jan 14; | doi: 10.1038/s41589-018-0213-2 | PMID: 30643282
Tóm tắt Chức năng
Anti-CRISPR-mediated control of gene editing and synthetic circuits in eukaryotic cells.
Nakamura M, Srinivasan P, Chavez M, Carter MA, Dominguez AA, La Russa M, Lau MB, Abbott TR, Xu X, Zhao D, Gao Y, Kipniss NH, Smolke CD, Bondy-Denomy J, Qi LS.
Nature communications. 2019 Jan 14;10(1):194 | doi: 10.1038/s41467-018-08158-x | PMID: 30643127 | PMC: PMC6331597
Tóm tắt Chức năng
The RNA-Binding Protein PUM2 Impairs Mitochondrial Dynamics and Mitophagy During Aging.
D'Amico D, Mottis A, Potenza F, Sorrentino V, Li H, Romani M, Lemos V, Schoonjans K, Zamboni N, Knott G, Schneider BL, Auwerx J.
Molecular cell. 2019 Jan 11; | doi: 10.1016/j.molcel.2018.11.034 | PMID: 30642763
Tóm tắt Chức năng
Current situation of biofuel production and its enhancement by CRISPR/Cas9-mediated genome engineering of microbial cells.
Javed MR, Noman M, Shahid M, Ahmed T, Khurshid M, Rashid MH, Ismail M, Sadaf M, Khan F.
Microbiological research. 2019 Feb;219:1-11 | doi: 10.1016/j.micres.2018.10.010 | PMID: 30642460
Tóm tắt Chức năng
ALS-linked FUS mutations confer loss and gain of function in the nucleus by promoting excessive formation of dysfunctional paraspeckles.
An H, Skelt L, Notaro A, Highley JR, Fox AH, La Bella V, Buchman VL, Shelkovnikova TA.
Acta neuropathologica communications. 2019 Jan 14;7(1):7 | doi: 10.1186/s40478-019-0658-x | PMID: 30642400 | PMC: PMC6330737
Tóm tắt Chức năng
Recent Advances in CRISPR/Cas9-Mediated Genome Editing in Dictyostelium.
Muramoto T, Iriki H, Watanabe J, Kawata T.
Cells. 2019 Jan 12;8(1) | doi: 10.3390/cells8010046 | PMID: 30642074
Tóm tắt Chức năng
HIF-1α and HIF-2α Differently Regulate the Radiation Sensitivity of NSCLC Cells.
Moreno Roig E, Groot AJ, Yaromina A, Hendrickx TC, Barbeau LMO, Giuranno L, Dams G, Ient J, Olivo Pimentel V, van Gisbergen MW, Dubois LJ, Vooijs MA.
Cells. 2019 Jan 12;8(1) | doi: 10.3390/cells8010045 | PMID: 30642030
Tóm tắt Chức năng
Recombinant turkey herpesvirus expressing H9 hemagglutinin providing protection against H9N2 avian influenza.
Liu L, Wang T, Wang M, Tong Q, Sun Y, Pu J, Sun H, Liu J.
Virology. 2019 Jan 4;529:7-15 | doi: 10.1016/j.virol.2019.01.004 | PMID: 30641481
Tóm tắt Chức năng
Programmable Molecular Scissors: Applications of a New Tool for Genome Editing in Biotech.
Saha SK, Saikot FK, Rahman MS, Jamal MAHM, Rahman SMK, Islam SMR, Kim KH.
Molecular therapy. Nucleic acids. 2018 Dec 6;14:212-238 | doi: 10.1016/j.omtn.2018.11.016 | PMID: 30641475
Tóm tắt Chức năng
Utilization of proliferable extracellular amastigotes for transient gene expression, drug sensitivity assay, and CRISPR/Cas9-mediated gene knockout in Trypanosoma cruzi.
Takagi Y, Akutsu Y, Doi M, Furukawa K.
PLoS neglected tropical diseases. 2019 Jan 14;13(1):e0007088 | doi: 10.1371/journal.pntd.0007088 | PMID: 30640901
Tóm tắt Chức năng
P53 ICE CRIM mouse: a tool to generate mutant allelic series in somatic cells and germ lines for cancer studies.
Fan HH, Yu IS, Lin YH, Wang SY, Liaw YH, Chen PL, Yang TL, Lin SW, Chen YT.
FASEB journal : official publication of the Federation of American Societies for Experimental Biology. 2019 Jan 14;:fj201802027R | doi: 10.1096/fj.201802027R | PMID: 30640520
Tóm tắt Chức năng
Precision control of CRISPR-Cas9 using small molecules and light.
Gangopadhyay SA, Cox K, Manna D, Lim D, Maji B, Zhou Q, Choudhary A.
Biochemistry. 2019 Jan 14; | doi: 10.1021/acs.biochem.8b01202 | PMID: 30640437
Tóm tắt Chức năng
Tafazzin-dependent cardiolipin composition in C6 glioma cells correlates with changes in mitochondrial and cellular functions, and cellular proliferation.
Gürtler S, Wolke C, Otto O, Heise N, Scholz F, Laporte A, Elsner M, Jörns A, Weinert S, Döring M, Jansing S, Gardemann A, Lendeckel U, Schild L.
Biochimica et biophysica acta. Molecular and cell biology of lipids. 2019 Jan 9; | doi: 10.1016/j.bbalip.2019.01.006 | PMID: 30639735
Tóm tắt Chức năng
Crystal Structures of Csm2 and Csm3 in the Type III-A CRISPR-Cas Effector Complex.
Takeshita D, Sato M, Inanaga H, Numata T.
Journal of molecular biology. 2019 Jan 10; | doi: 10.1016/j.jmb.2019.01.009 | PMID: 30639408
Tóm tắt Chức năng
The Functional Proximal Proteome of Oncogenic Ras Includes mTORC2.
Kovalski JR, Bhaduri A, Zehnder AM, Neela PH, Che Y, Wozniak GG, Khavari PA.
Molecular cell. 2019 Jan 4; | doi: 10.1016/j.molcel.2018.12.001 | PMID: 30639242
Tóm tắt Chức năng
Mechanistic Insights into the cis- and trans-Acting DNase Activities of Cas12a.
Swarts DC, Jinek M.
Molecular cell. 2018 Dec 20; | doi: 10.1016/j.molcel.2018.11.021 | PMID: 30639240
Tóm tắt Chức năng
OVOL1 Influences the Determination and Expansion of iPSC Reprogramming Intermediates.
Kagawa H, Shimamoto R, Kim SI, Oceguera-Yanez F, Yamamoto T, Schroeder T, Woltjen K.
Stem cell reports. 2018 Dec 28; | doi: 10.1016/j.stemcr.2018.12.008 | PMID: 30639212
Tóm tắt Chức năng
Patient-Specific iPSC-Derived Astrocytes Contribute to Non-Cell-Autonomous Neurodegeneration in Parkinson's Disease.
di Domenico A, Carola G, Calatayud C, Pons-Espinal M, Muñoz JP, Richaud-Patin Y, Fernandez-Carasa I, Gut M, Faella A, Parameswaran J, Soriano J, Ferrer I, Tolosa E, Zorzano A, Cuervo AM, Raya A, Consiglio A.
Stem cell reports. 2019 Jan 6; | doi: 10.1016/j.stemcr.2018.12.011 | PMID: 30639209
Tóm tắt Chức năng
Genome-wide CRISPR Screens in T Helper Cells Reveal Pervasive Crosstalk between Activation and Differentiation.
Henriksson J, Chen X, Gomes T, Ullah U, Meyer KB, Miragaia R, Duddy G, Pramanik J, Yusa K, Lahesmaa R, Teichmann SA.
Cell. 2019 Jan 7; | doi: 10.1016/j.cell.2018.11.044 | PMID: 30639098
Tóm tắt Chức năng
Patient Adipose Stem Cell-Derived Adipocytes Reveal Genetic Variation that Predicts Antidiabetic Drug Response.
Hu W, Jiang C, Guan D, Dierickx P, Zhang R, Moscati A, Nadkarni GN, Steger DJ, Loos RJF, Hu C, Jia W, Soccio RE, Lazar MA.
Cell stem cell. 2018 Dec 23; | doi: 10.1016/j.stem.2018.11.018 | PMID: 30639037
Tóm tắt Chức năng
Allosteric Feedback Inhibition Enables Robust Amino Acid Biosynthesis in E. coli by Enforcing Enzyme Overabundance.
Sander T, Farke N, Diehl C, Kuntz M, Glatter T, Link H.
Cell systems. 2019 Jan 4; | doi: 10.1016/j.cels.2018.12.005 | PMID: 30638812
Tóm tắt Chức năng
A Customizable Protocol for String Assembly gRNA Cloning (STAgR).
Breunig CT, Neuner AM, Giehrl-Schwab J, Wurst W, Götz M, Stricker SH.
Journal of visualized experiments : JoVE. 2018 Dec 26;(142) | doi: 10.3791/58556 | PMID: 30638198
Tóm tắt Chức năng
Tn antigen promotes human colorectal cancer metastasis via H-Ras mediated epithelial-mesenchymal transition activation.
Liu Z, Liu J, Dong X, Hu X, Jiang Y, Li L, Du T, Yang L, Wen T, An G, Feng G.
Journal of cellular and molecular medicine. 2019 Jan 13; | doi: 10.1111/jcmm.14117 | PMID: 30637914
Tóm tắt Chức năng
Establishment and characterization of an immortalized renal cell line of the Chinese tree shrew (Tupaia belangeri chinesis).
Gu T, Yu D, Li Y, Xu L, Yao YL, Yao YG.
Applied microbiology and biotechnology. 2019 Jan 12; | doi: 10.1007/s00253-019-09615-3 | PMID: 30637496
Tóm tắt Chức năng
Marine Sponges as Chloroflexi Hot Spots: Genomic Insights and High-Resolution Visualization of an Abundant and Diverse Symbiotic Clade.
Bayer K, Jahn MT, Slaby BM, Moitinho-Silva L, Hentschel U.
mSystems. 2018 Nov-Dec;3(6) | doi: 10.1128/mSystems.00150-18 | PMID: 30637337 | PMC: PMC6306507
Tóm tắt Chức năng
CRISPR-Cas9 a boon or bane: the bumpy road ahead to cancer therapeutics.
Ghosh D, Venkataramani P, Nandi S, Bhattacharjee S.
Cancer cell international. 2019;19:12 | doi: 10.1186/s12935-019-0726-0 | PMID: 30636933 | PMC: PMC6325665
Tóm tắt Chức năng
Combining Orthogonal CRISPR and CRISPRi Systems for Genome Engineering and Metabolic Pathway Modulation in E. coli.
Sung LY, Wu MY, Lin MW, Hsu MN, Truong VA, Shen CC, Tu Y, Hwang KY, Tu AP, Chang YH, Hu YC.
Biotechnology and bioengineering. 2019 Jan 13; | doi: 10.1002/bit.26915 | PMID: 30636321
Tóm tắt Chức năng
Distinct timescales of RNA regulators enable the construction of a genetic pulse generator.
Westbrook A, Tang X, Marshall R, Maxwell CS, Chappell J, Agrawal DK, Dunlop MJ, Noireaux V, Beisel CL, Lucks J, Franco E.
Biotechnology and bioengineering. 2019 Jan 13; | doi: 10.1002/bit.26918 | PMID: 30636320
Tóm tắt Chức năng
POLQ plays a key role in repair of CRISPR/Cas9 induced double strand breaks in the moss Physcomitrella patens.
Mara K, Charlot F, Guyon-Debast A, Schaefer DG, Collonnier C, Grelon M, Nogué F.
The New phytologist. 2019 Jan 13; | doi: 10.1111/nph.15680 | PMID: 30636294
Tóm tắt Chức năng
Transplacental Delivery of Genome Editing Components Causes Mutations in Embryonic Cardiomyocytes of Mid-Gestational Murine Fetuses.
Nakamura S, Ishihara M, Ando N, Watanabe S, Sakurai T, Sato M.
IUBMB life. 2019 Jan 11; | doi: 10.1002/iub.2004 | PMID: 30635953
Tóm tắt Chức năng
Micronemal protein 13 contributes to the optimal growth of Toxoplasma gondii under stress conditions.
Ye S, Xia N, Zhao P, Yang J, Zhou Y, Shen B, Zhao J.
Parasitology research. 2019 Jan 11; | doi: 10.1007/s00436-018-06197-3 | PMID: 30635773
Tóm tắt Chức năng
Characterization and distribution of CRISPR-Cas systems in Lactobacillus sakei.
Schuster JA, Vogel RF, Ehrmann MA.
Archives of microbiology. 2019 Jan 11; | doi: 10.1007/s00203-019-01619-x | PMID: 30635671
Tóm tắt Chức năng
Chk1-mediated Cdc25A degradation as a critical mechanism for normal cell-cycle progression.
Goto H, Natsume T, Kanemaki MT, Kaito A, Wang S, Gabazza EC, Inagaki M, Mizoguchi A.
Journal of cell science. 2019 Jan 11; | doi: 10.1242/jcs.223123 | PMID: 30635443
Tóm tắt Chức năng
Initial characterization of Wnt-Tcf functions during Ciona heart development.
Kaplan NA, Wang W, Christiaen L.
Developmental biology. 2019 Jan 8; | doi: 10.1016/j.ydbio.2018.12.018 | PMID: 30635127
Tóm tắt Chức năng
Heme oxygenase 1 facilitates cell proliferation via the B-Raf-ERK signaling pathway in melanoma.
Liu L, Wu Y, Bian C, Nisar MF, Wang M, Hu X, Diao Q, Nian W, Wang E, Xu W, Zhong JL.
Cell communication and signaling : CCS. 2019 Jan 11;17(1):3 | doi: 10.1186/s12964-018-0313-3 | PMID: 30634993 | PMC: PMC6329143
Tóm tắt Chức năng
Generation of two iPSC lines with either a heterozygous V717I or a heterozygous KM670/671NL mutation in the APP gene.
Frederiksen HR, Holst B, Ramakrishna S, Muddashetty R, Schmid B, Freude K.
Stem cell research. 2018 Dec 24;34:101368 | doi: 10.1016/j.scr.2018.101368 | PMID: 30634129
Tóm tắt Chức năng
Phage serine integrase-mediated genome engineering for efficient expression of chemical biosynthetic pathway in gas-fermenting Clostridium ljungdahlii.
Huang H, Chai C, Yang S, Jiang W, Gu Y.
Metabolic engineering. 2019 Jan 8;52:293-302 | doi: 10.1016/j.ymben.2019.01.005 | PMID: 30633974
Tóm tắt Chức năng
The histone H3 Lys 27 demethylase KDM6B promotes migration and invasion of glioma cells partly by regulating the expression of SNAI1.
Sui A, Xu Y, Yang J, Pan B, Wu J, Guo T, Shen Y, Guo X.
Neurochemistry international. 2019 Jan 8;124:123-129 | doi: 10.1016/j.neuint.2019.01.006 | PMID: 30633952
Tóm tắt Chức năng
CRISPR-Cas9 Circular Permutants as Programmable Scaffolds for Genome Modification.
Oakes BL, Fellmann C, Rishi H, Taylor KL, Ren SM, Nadler DC, Yokoo R, Arkin AP, Doudna JA, Savage DF.
Cell. 2019 Jan 10;176(1-2):254-267.e16 | doi: 10.1016/j.cell.2018.11.052 | PMID: 30633905
Tóm tắt Chức năng
Developmental and comparative transcriptomic identification of iridophore contribution to white barring in clownfish.
Salis P, Lorin T, Lewis V, Rey C, Marcionetti A, Escande ML, Roux N, Besseau L, Salamin N, Sémon M, Parichy D, Volff JN, Laudet V.
Pigment cell & melanoma research. 2019 Jan 11; | doi: 10.1111/pcmr.12766 | PMID: 30633441
Tóm tắt Chức năng
Creating highly efficient resistance against Wheat dwarf virus in barley by employing CRISPR/Cas9 system.
Kis A, Hamar É, Tholt G, Bán R, Havelda Z.
Plant biotechnology journal. 2019 Jan 11; | doi: 10.1111/pbi.13077 | PMID: 30633425
Tóm tắt Chức năng
CRISPR-based RNA editing: diagnostic applications and therapeutic options.
Gulei D, Raduly L, Berindan-Neagoe I, Calin GA.
Expert review of molecular diagnostics. 2019 Jan 11;:1-6 | doi: 10.1080/14737159.2019.1568242 | PMID: 30632384
Tóm tắt Chức năng
Milestones achieved in response to drought stress through reverse genetic approaches.
Singh B, Kukreja S, Goutam U.
F1000Research. 2018;7:1311 | doi: 10.12688/f1000research.15606.1 | PMID: 30631439 | PMC: PMC6290974
Tóm tắt Chức năng
LncRNAs-directed PTEN enzymatic switch governs epithelial-mesenchymal transition.
Hu Q, Li C, Wang S, Li Y, Wen B, Zhang Y, Liang K, Yao J, Ye Y, Hsiao H, Nguyen TK, Park PK, Egranov SD, Hawke DH, Marks JR, Han L, Hung MC, Zhang B, Lin C, Yang L.
Cell research. 2019 Jan 10; | doi: 10.1038/s41422-018-0134-3 | PMID: 30631154
Tóm tắt Chức năng
Defective AP-3-dependent VAMP8 trafficking impairs Weibel-Palade body exocytosis in Hermansky-Pudlak Syndrome type 2 blood outgrowth endothelial cells.
Karampini E, Schillemans M, Hofman M, van Alphen F, de Boer M, Kuijpers TW, van den Biggelaar M, Voorberg J, Bierings R.
Haematologica. 2019 Jan 10; | doi: 10.3324/haematol.2018.207787 | PMID: 30630984
Tóm tắt Chức năng
Corilagin alleviates acetaminophen-induced hepatotoxicity via enhancing the AMPK/GSK3β-Nrf2 signaling pathway.
Lv H, Hong L, Tian Y, Yin C, Zhu C, Feng H.
Cell communication and signaling : CCS. 2019 Jan 10;17(1):2 | doi: 10.1186/s12964-018-0314-2 | PMID: 30630510 | PMC: PMC6327405
Tóm tắt Chức năng
Towards an understanding of C9orf82 protein/CAAP1 function.
Aslam MA, Alemdehy MF, Pritchard CEJ, Song JY, Muhaimin FI, Wijdeven RH, Huijbers IJ, Neefjes J, Jacobs H.
PloS one. 2019;14(1):e0210526 | doi: 10.1371/journal.pone.0210526 | PMID: 30629682
Tóm tắt Chức năng
Novel strategies to target PCSK9: beyond monoclonal antibodies.
Seidah NG, Prat A, Pirillo A, Luigi Catapano A, Danilo Norata G.
Cardiovascular research. 2019 Jan 10; | doi: 10.1093/cvr/cvz003 | PMID: 30629143
Tóm tắt Chức năng
Aberrant RNA splicing is the major pathogenic effect in a knock-in mouse model of the dominantly inherited c.1430A>G human RPE65 mutation.
Li Y, Furhang R, Ray A, Duncan T, Soucy J, Mahdi R, Chaitankar V, Gieser L, Poliakov E, Qian H, Liu P, Dong L, Rogozin IB, Redmond TM.
Human mutation. 2019 Jan 10; | doi: 10.1002/humu.23706 | PMID: 30628748
Tóm tắt Chức năng
Using CRISPR/Cas9 engineering to generate a mouse with a conditional knockout allele for the promyelocytic leukemia zinc finger transcription factor.
Hai L, Szwarc MM, Lanza DG, Heaney JD, Lydon JP.
Genesis (New York, N.Y. : 2000). 2019 Jan 9;:e23281 | doi: 10.1002/dvg.23281 | PMID: 30628160
Tóm tắt Chức năng
The basic helix-loop-helix transcription factor, OsPIL15 regulates grain size via directly targeting a purine permease gene OsPUP7 in rice.
Ji X, Du Y, Li F, Sun H, Zhang J, Li J, Peng T, Xin Z, Zhao Q.
Plant biotechnology journal. 2019 Jan 9; | doi: 10.1111/pbi.13075 | PMID: 30628157
Tóm tắt Chức năng
Redkmer: An Assembly-Free Pipeline for the Identification of Abundant and Specific X-Chromosome Target Sequences for X-Shredding by CRISPR Endonucleases.
Papathanos PA, Windbichler N.
The CRISPR journal. 2018 Feb 1;1(1):88-98 | doi: 10.1089/crispr.2017.0012 | PMID: 30627701 | PMC: PMC6319322
Tóm tắt Chức năng
Transgenerational CRISPR-Cas9 Activity Facilitates Multiplex Gene Editing in Allopolyploid Wheat.
Wang W, Pan Q, He F, Akhunova A, Chao S, Trick H, Akhunov E.
The CRISPR journal. 2018 Feb 1;1(1):65-74 | doi: 10.1089/crispr.2017.0010 | PMID: 30627700 | PMC: PMC6319321
Tóm tắt Chức năng
Pathogenomics of Virulence Traits of Plesiomonas shigelloides That Were Deemed Inconclusive by Traditional Experimental Approaches.
Ekundayo TC, Okoh AI.
Frontiers in microbiology. 2018;9:3077 | doi: 10.3389/fmicb.2018.03077 | PMID: 30627119 | PMC: PMC6309461
Tóm tắt Chức năng
Identification of clotrimazole-derivatives as specific inhibitors of Arenavirus fusion.
Torriani G, Trofimenko E, Mayor J, Fedeli C, Moreno H, Michel S, Heulot M, Chevalier N, Zimmer G, Shrestha N, Plattet P, Engler O, Rothenberger S, Widmann C, Kunz S.
Journal of virology. 2019 Jan 9; | doi: 10.1128/JVI.01744-18 | PMID: 30626681
Tóm tắt Chức năng
Generating mouse models for biomedical research: technological advances.
Gurumurthy CB, Lloyd KCK.
Disease models & mechanisms. 2019 Jan 8;12(1) | doi: 10.1242/dmm.029462 | PMID: 30626588
Tóm tắt Chức năng
Zebrafish as a model system to delineate the role of heme and iron metabolism during erythropoiesis.
Zhang J, Hamza I.
Molecular genetics and metabolism. 2018 Dec 24; | doi: 10.1016/j.ymgme.2018.12.007 | PMID: 30626549
Tóm tắt Chức năng
Fast gene disruption in Trichoderma reesei using in vitro assembled Cas9/gRNA complex.
Hao Z, Su X.
BMC biotechnology. 2019 Jan 9;19(1):2 | doi: 10.1186/s12896-018-0498-y | PMID: 30626373 | PMC: PMC6325762
Tóm tắt Chức năng
The Wnt-Driven Mll1 Epigenome Regulates Salivary Gland and Head and Neck Cancer.
Zhu Q, Fang L, Heuberger J, Kranz A, Schipper J, Scheckenbach K, Vidal RO, Sunaga-Franze DY, Müller M, Wulf-Goldenberg A, Sauer S, Birchmeier W.
Cell reports. 2019 Jan 8;26(2):415-428.e5 | doi: 10.1016/j.celrep.2018.12.059 | PMID: 30625324
Tóm tắt Chức năng
Optimization of T-DNA architecture for Cas9-mediated mutagenesis in Arabidopsis.
Castel B, Tomlinson L, Locci F, Yang Y, Jones JDG.
PloS one. 2019;14(1):e0204778 | doi: 10.1371/journal.pone.0204778 | PMID: 30625150 | PMC: PMC6326418
Tóm tắt Chức năng
Reducing phenolic off-flavors through CRISPR-based gene editing of the FDC1 gene in Saccharomyces cerevisiae x Saccharomyces eubayanus hybrid lager beer yeasts.
Mertens S, Gallone B, Steensels J, Herrera-Malaver B, Cortebeek J, Nolmans R, Saels V, Vyas VK, Verstrepen KJ.
PloS one. 2019;14(1):e0209124 | doi: 10.1371/journal.pone.0209124 | PMID: 30625138 | PMC: PMC6326464
Tóm tắt Chức năng
Mutagenesis of putative ciliary genes with the CRISPR/Cas9 system in zebrafish identifies genes required for retinal development.
Hu R, Huang W, Liu J, Jin M, Wu Y, Li J, Wang J, Yu Z, Wang H, Cao Y.
FASEB journal : official publication of the Federation of American Societies for Experimental Biology. 2019 Jan 9;:fj201802140R | doi: 10.1096/fj.201802140R | PMID: 30624971
Tóm tắt Chức năng
Identification of NFAT5 as a transcriptional regulator of the EDN1gene in collecting duct.
Lakshmipathi J, Wheatley W, Kumar A, Mercenne G, Rodan AR, Kohan DE.
American journal of physiology. Renal physiology. 2019 Jan 9; | doi: 10.1152/ajprenal.00509.2018 | PMID: 30623723
Tóm tắt Chức năng
Developing disease-resistant thermosensitive male sterile rice by multiplex gene editing.
Li S, Shen L, Hu P, Liu Q, Zhu X, Qian Q, Wang K, Wang Y.
Journal of integrative plant biology. 2019 Jan 8; | doi: 10.1111/jipb.12774 | PMID: 30623600
Tóm tắt Chức năng
Disabling of nephrogenesis in porcine embryos via CRISPR/Cas9-mediated SIX1 and SIX4 gene targeting.
Wang J, Liu M, Zhao L, Li Y, Zhang M, Jin Y, Xiong Q, Liu X, Zhang L, Jiang H, Chen Q, Wang C, You Z, Yang H, Cao C, Dai Y, Li R.
Xenotransplantation. 2019 Jan 9;:e12484 | doi: 10.1111/xen.12484 | PMID: 30623494
Tóm tắt Chức năng
Principles of gene editing techniques and applications in animal husbandry.
Jiang S, Shen QW.
3 Biotech. 2019 Jan;9(1):28 | doi: 10.1007/s13205-018-1563-x | PMID: 30622866 | PMC: PMC6318154
Tóm tắt Chức năng
Revisiting Risk Governance of GM Plants: The Need to Consider New and Emerging Gene-Editing Techniques.
Agapito-Tenfen SZ, Okoli AS, Bernstein MJ, Wikmark OG, Myhr AI.
Frontiers in plant science. 2018;9:1874 | doi: 10.3389/fpls.2018.01874 | PMID: 30622546 | PMC: PMC6308909
Tóm tắt Chức năng
A Sox2-Sox9 signalling axis maintains human breast luminal progenitor and breast cancer stem cells.
Domenici G, Aurrekoetxea-Rodríguez I, Simões BM, Rábano M, Lee SY, Millán JS, Comaills V, Oliemuller E, López-Ruiz JA, Zabalza I, Howard BA, Kypta RM, Vivanco MD.
Oncogene. 2019 Jan 8; | doi: 10.1038/s41388-018-0656-7 | PMID: 30622340
Tóm tắt Chức năng
Biallelic sequence variants in INTS1 in patients with developmental delays, cataracts, and craniofacial anomalies.
Krall M, Htun S, Schnur RE, Brooks AS, Baker L, de Alba Campomanes A, Lamont RE, Gripp KW, Care 4 Rare Canada Consortium., Schneidman-Duhovny D, Innes AM, Mancini GMS, Slavotinek AM.
European journal of human genetics : EJHG. 2019 Jan 8; | doi: 10.1038/s41431-018-0298-9 | PMID: 30622326
Tóm tắt Chức năng
Transforming insect population control with precision guided sterile males with demonstration in flies.
Kandul NP, Liu J, Sanchez C HM, Wu SL, Marshall JM, Akbari OS.
Nature communications. 2019 Jan 8;10(1):84 | doi: 10.1038/s41467-018-07964-7 | PMID: 30622266 | PMC: PMC6325135
Tóm tắt Chức năng
ATM orchestrates the DNA-damage response to counter toxic non-homologous end-joining at broken replication forks.
Balmus G, Pilger D, Coates J, Demir M, Sczaniecka-Clift M, Barros AC, Woods M, Fu B, Yang F, Chen E, Ostermaier M, Stankovic T, Ponstingl H, Herzog M, Yusa K, Martinez FM, Durant ST, Galanty Y, Beli P, Adams DJ, Bradley A, Metzakopian E, Forment JV, Jackson SP.
Nature communications. 2019 Jan 8;10(1):87 | doi: 10.1038/s41467-018-07729-2 | PMID: 30622252 | PMC: PMC6325118
Tóm tắt Chức năng
Fluorescent labeling of CRISPR/Cas9 RNP for gene knockout in HSPCs and iPSCs reveals an essential role for GADD45b in stress response.
Nasri M, Mir P, Dannenmann B, Amend D, Skroblyn T, Xu Y, Schulze-Osthoff K, Klimiankou M, Welte K, Skokowa J.
Blood advances. 2019 Jan 8;3(1):63-71 | doi: 10.1182/bloodadvances.2017015511 | PMID: 30622144 | PMC: PMC6325296
Tóm tắt Chức năng
HER2 CAR-T cells eradicate uveal melanoma and T cell therapy-resistant human melanoma in interleukin-2 (IL-2) transgenic NOD/SCID IL-2 receptor knockout mice.
Forsberg EM, Lindberg MF, Jespersen H, Alsén S, Olofsson Bagge R, Donia M, Svane IM, Nilsson O, Ny L, Nilsson LM, Nilsson JA.
Cancer research. 2019 Jan 8; | doi: 10.1158/0008-5472.CAN-18-3158 | PMID: 30622115
Tóm tắt Chức năng
Gene-edited CRISPy Critters for alcohol research.
Homanics GE.
Alcohol (Fayetteville, N.Y.). 2019 Feb;74:11-19 | doi: 10.1016/j.alcohol.2018.03.001 | PMID: 30621855 | PMC: PMC6334660
Tóm tắt Chức năng
Systematic evaluation of C. elegans lincRNAs with CRISPR knockout mutants.
Wei S, Chen H, Dzakah EE, Yu B, Wang X, Fu T, Li J, Liu L, Fang S, Liu W, Shan G.
Genome biology. 2019 Jan 8;20(1):7 | doi: 10.1186/s13059-018-1619-6 | PMID: 30621757 | PMC: PMC6325887
Tóm tắt Chức năng
Viral Delivery Systems for CRISPR.
Xu CL, Ruan MZC, Mahajan VB, Tsang SH.
Viruses. 2019 Jan 4;11(1) | doi: 10.3390/v11010028 | PMID: 30621179
Tóm tắt Chức năng
Restoring Dystrophin Expression in Duchenne Muscular Dystrophy: Current Status of Therapeutic Approaches.
Shimizu-Motohashi Y, Komaki H, Motohashi N, Takeda S, Yokota T, Aoki Y.
Journal of personalized medicine. 2019 Jan 7;9(1) | doi: 10.3390/jpm9010001 | PMID: 30621068
Tóm tắt Chức năng
CRISPR-Based Subtyping Using Whole Genome Sequence Data Does Not Improve Differentiation of Persistent and Sporadic Listeria monocytogenes Strains.
Taylor AJ, Stasiewicz MJ.
Journal of food science. 2019 Jan 8; | doi: 10.1111/1750-3841.14426 | PMID: 30620778
Tóm tắt Chức năng
EPHA5 mediates trastuzumab resistance in HER2-positive breast cancers through regulating cancer stem cell-like properties.
Li Y, Chu J, Feng W, Yang M, Zhang Y, Zhang Y, Qin Y, Xu J, Li J, Vasilatos SN, Fu Z, Huang Y, Yin Y.
FASEB journal : official publication of the Federation of American Societies for Experimental Biology. 2019 Jan 8;:fj201701561RRRR | doi: 10.1096/fj.201701561RRRR | PMID: 30620624
Tóm tắt Chức năng
DEGS1-associated aberrant sphingolipid metabolism impairs nervous system function in humans.
Karsai G, Kraft F, Haag N, Korenke GC, Hänisch B, Othman A, Suriyanarayanan S, Steiner R, Knopp C, Mull M, Bergmann M, Schröder JM, Weis J, Elbracht M, Begemann M, Hornemann T, Kurth I.
The Journal of clinical investigation. 2019 Jan 8; | doi: 10.1172/JCI124159 | PMID: 30620338
Tóm tắt Chức năng
Individual long non-coding RNAs have no overt functions in zebrafish embryogenesis, viability and fertility.
Goudarzi M, Berg K, Pieper LM, Schier AF.
eLife. 2019 Jan 8;8 | doi: 10.7554/eLife.40815 | PMID: 30620332
Tóm tắt Chức năng
A Self-Deleting AAV-CRISPR System for In Vivo Genome Editing.
Li A, Lee CM, Hurley AE, Jarrett KE, De Giorgi M, Lu W, Balderrama KS, Doerfler AM, Deshmukh H, Ray A, Bao G, Lagor WR.
Molecular therapy. Methods & clinical development. 2019 Mar 15;12:111-122 | doi: 10.1016/j.omtm.2018.11.009 | PMID: 30619914 | PMC: PMC6313841
Tóm tắt Chức năng
Normative Criteria and Their Inclusion in a Regulatory Framework for New Plant Varieties Derived From Genome Editing.
Hamburger DJS.
Frontiers in bioengineering and biotechnology. 2018;6:176 | doi: 10.3389/fbioe.2018.00176 | PMID: 30619841 | PMC: PMC6305715
Tóm tắt Chức năng
Infantile Neuroaxonal Dystrophy: Diagnosis and Possible Treatments.
Babin PL, Rao SNR, Chacko A, Alvina FB, Panwala A, Panwala L, Fumagalli DC.
Frontiers in genetics. 2018;9:597 | doi: 10.3389/fgene.2018.00597 | PMID: 30619446 | PMC: PMC6295457
Tóm tắt Chức năng
Identification of LncRNA Linc00513 Containing Lupus-Associated Genetic Variants as a Novel Regulator of Interferon Signaling Pathway.
Xue Z, Cui C, Liao Z, Xia S, Zhang P, Qin J, Guo Q, Chen S, Fu Q, Yin Z, Ye Z, Tang Y, Shen N.
Frontiers in immunology. 2018;9:2967 | doi: 10.3389/fimmu.2018.02967 | PMID: 30619325 | PMC: PMC6305415
Tóm tắt Chức năng
Iron Regulation in Clostridioides difficile.
Berges M, Michel AM, Lassek C, Nuss AM, Beckstette M, Dersch P, Riedel K, Sievers S, Becher D, Otto A, Maaß S, Rohde M, Eckweiler D, Borrero-de Acuña JM, Jahn M, Neumann-Schaal M, Jahn D.
Frontiers in microbiology. 2018;9:3183 | doi: 10.3389/fmicb.2018.03183 | PMID: 30619231 | PMC: PMC6311696
Tóm tắt Chức năng
CRISPR/Cas9 Genome Editing to Disable the Latent HIV-1 Provirus.
Panfil AR, London JA, Green PL, Yoder KE.
Frontiers in microbiology. 2018;9:3107 | doi: 10.3389/fmicb.2018.03107 | PMID: 30619186 | PMC: PMC6302043
Tóm tắt Chức năng
Gene Editing of HIV-1 Co-receptors to Prevent and/or Cure Virus Infection.
Allen AG, Chung CH, Atkins A, Dampier W, Khalili K, Nonnemacher MR, Wigdahl B.
Frontiers in microbiology. 2018;9:2940 | doi: 10.3389/fmicb.2018.02940 | PMID: 30619107 | PMC: PMC6304358
Tóm tắt Chức năng
Genetic Models of Calpain Deficiency and Ectopic Expression.
Gao Y, Hall C, MacLeod J, Greer PA.
Methods in molecular biology (Clifton, N.J.). 2019;1915:261-274 | doi: 10.1007/978-1-4939-8988-1_20 | PMID: 30617810
Tóm tắt Chức năng
Enabling genetic analysis of diverse bacteria with Mobile-CRISPRi.
Peters JM, Koo BM, Patino R, Heussler GE, Hearne CC, Qu J, Inclan YF, Hawkins JS, Lu CHS, Silvis MR, Harden MM, Osadnik H, Peters JE, Engel JN, Dutton RJ, Grossman AD, Gross CA, Rosenberg OS.
Nature microbiology. 2019 Jan 7; | doi: 10.1038/s41564-018-0327-z | PMID: 30617347
Tóm tắt Chức năng
Development of immunocompatible pluripotent stem cells via CRISPR-based human leukocyte antigen engineering.
Jang Y, Choi J, Park N, Kang J, Kim M, Kim Y, Ju JH.
Experimental & molecular medicine. 2019 Jan 7;51(1):3 | doi: 10.1038/s12276-018-0190-2 | PMID: 30617277 | PMC: PMC6323054
Tóm tắt Chức năng
microRNA-22 promotes megakaryocyte differentiation through repression of its target, GFI1.
Weiss CN, Ito K.
Blood advances. 2019 Jan 8;3(1):33-46 | doi: 10.1182/bloodadvances.2018023804 | PMID: 30617215 | PMC: PMC6325298
Tóm tắt Chức năng
A natural regulatory mutation in the proximal promoter elevates fetal globin expression by creating a de novo GATA1 site.
Martyn GE, Wienert B, Kurita R, Nakamura Y, Quinlan KGR, Crossley M.
Blood. 2019 Jan 7; | doi: 10.1182/blood-2018-07-863951 | PMID: 30617196
Tóm tắt Chức năng
Genetic manipulation of PLB-985 cells and quantification of chemotaxis using the underagarose assay.
Saunders CA, Majumdar R, Molina Y, Subramanian BC, Parent CA.
Methods in cell biology. 2019;149:31-56 | doi: 10.1016/bs.mcb.2018.09.002 | PMID: 30616826
Tóm tắt Chức năng
A Road Map to Personalizing Targeted Cancer Therapies Using Synthetic Lethality.
Parameswaran S, Kundapur D, Vizeacoumar FS, Freywald A, Uppalapati M, Vizeacoumar FJ.
Trends in cancer. 2019 Jan;5(1):11-29 | doi: 10.1016/j.trecan.2018.11.001 | PMID: 30616753
Tóm tắt Chức năng
Human-like NSG mouse glycoproteins sialylation pattern changes the phenotype of human lymphocytes and sensitivity to HIV-1 infection.
Dagur RS, Branch-Woods A, Mathews S, Joshi PS, Quadros RM, Harms DW, Cheng Y, Miles SM, Pirruccello SJ, Gurumurthy CB, Gorantla S, Poluektova LY.
BMC immunology. 2019 Jan 7;20(1):2 | doi: 10.1186/s12865-018-0279-3 | PMID: 30616506 | PMC: PMC6322283
Tóm tắt Chức năng
CRISPR/Cas9-based genome-editing in the filamentous fungus Fusarium fujikuroi and its application in strain engineering for gibberellic acid production.
Shi TQ, Gao J, Wang WJ, Wang KF, Xu GQ, Huang H, Ji XJ.
ACS synthetic biology. 2019 Jan 7; | doi: 10.1021/acssynbio.8b00478 | PMID: 30616338
Tóm tắt Chức năng
[Application of clustered regularly interspaced short palindromic repeats- associated protein 9 gene editing technology for treatment of HBV infection].
Wang YD, Liang QF, Li ZY, Zhao CY.
Zhonghua gan zang bing za zhi = Zhonghua ganzangbing zazhi = Chinese journal of hepatology. 2018 Nov 20;26(11):860-864 | doi: 10.3760/cma.j.issn.1007-3418.2018.11.012 | PMID: 30616324
Tóm tắt Chức năng
The Gata2 repression during 3T3-L1 preadipocyte differentiation is dependent on a rapid decrease in histone acetylation in response to glucocorticoid receptor activation.
Ishijima Y, Ohmori S, Uneme A, Aoki Y, Kobori M, Ohida T, Arai M, Hosaka M, Ohneda K.
Molecular and cellular endocrinology. 2019 Jan 4; | doi: 10.1016/j.mce.2019.01.002 | PMID: 30615908
Tóm tắt Chức năng
CRISPR-Cas9 In Situ engineering of subtilisin E in Bacillus subtilis.
Price MA, Cruz R, Baxter S, Escalettes F, Rosser SJ.
PloS one. 2019;14(1):e0210121 | doi: 10.1371/journal.pone.0210121 | PMID: 30615645 | PMC: PMC6322745
Tóm tắt Chức năng
Deep learning image recognition enables efficient genome editing in zebrafish by automated injections.
Cordero-Maldonado ML, Perathoner S, van der Kolk KJ, Boland R, Heins-Marroquin U, Spaink HP, Meijer AH, Crawford AD, de Sonneville J.
PloS one. 2019;14(1):e0202377 | doi: 10.1371/journal.pone.0202377 | PMID: 30615627 | PMC: PMC6322765
Tóm tắt Chức năng
The microRNA, miR-18a, regulates NeuroD and photoreceptor differentiation in the retina of the zebrafish.
Taylor SM, Giuffre E, Moseley P, Hitchcock PF.
Developmental neurobiology. 2019 Jan 7; | doi: 10.1002/dneu.22666 | PMID: 30615274
Tóm tắt Chức năng
CRISPR-DT: designing gRNAs for the CRISPR-Cpf1 system with improved target efficiency and specificity.
Zhu H, Liang C.
Bioinformatics (Oxford, England). 2019 Jan 7; | doi: 10.1093/bioinformatics/bty1061 | PMID: 30615056
Tóm tắt Chức năng
Experiments that led to the first gene-edited babies: the ethical failings and the urgent need for better governance.
Li JR, Walker S, Nie JB, Zhang XQ.
Journal of Zhejiang University. Science. B. 2019 Jan.;20(1):32-38 | doi: 10.1631/jzus.B1800624 | PMID: 30614228
Tóm tắt Chức năng
Making gene editing a therapeutic reality.
Conboy I, Murthy N, Etienne J, Robinson Z.
F1000Research. 2018;7 | doi: 10.12688/f1000research.16106.1 | PMID: 30613384 | PMC: PMC6305220
Tóm tắt Chức năng
An azoospermic factor gene, Ddx3y and its paralog, Ddx3x are dispensable in germ cells for male fertility.
Matsumura T, Endo T, Isotani A, Ogawa M, Ikawa M.
The Journal of reproduction and development. 2019 Jan 7; | doi: 10.1262/jrd.2018-145 | PMID: 30613052
Tóm tắt Chức năng
A Genome-wide Framework for Mapping Gene Regulation via Cellular Genetic Screens.
Gasperini M, Hill AJ, McFaline-Figueroa JL, Martin B, Kim S, Zhang MD, Jackson D, Leith A, Schreiber J, Noble WS, Trapnell C, Ahituv N, Shendure J.
Cell. 2019 Jan 10;176(1-2):377-390.e19 | doi: 10.1016/j.cell.2018.11.029 | PMID: 30612741
Tóm tắt Chức năng
De Novo Variants in MAPK8IP3 Cause Intellectual Disability with Variable Brain Anomalies.
Platzer K, Sticht H, Edwards SL, Allen W, Angione KM, Bonati MT, Brasington C, Cho MT, Demmer LA, Falik-Zaccai T, Gamble CN, Hellenbroich Y, Iascone M, Kok F, Mahida S, Mandel H, Marquardt T, McWalter K, Panis B, Pepler A, Pinz H, Ramos L, Shinde DN, Smith-Hicks C, Stegmann APA, Stöbe P, Stumpel CTRM, Wilson C, Lemke JR, Di Donato N, Miller KG, Jamra R.
American journal of human genetics. 2018 Dec 31; | doi: 10.1016/j.ajhg.2018.12.008 | PMID: 30612693
Tóm tắt Chức năng
Recessive mutation in CD2AP causes focal segmental glomerulosclerosis in humans and mice.
Takano T, Bareke E, Takeda N, Aoudjit L, Baldwin C, Pisano P, Matsuda J, El Andalousi J, Muhtadie L, Bernard C, Majewski J, Miyazaki T, Yamamura KI, Gupta IR.
Kidney international. 2019 Jan;95(1):57-61 | doi: 10.1016/j.kint.2018.08.014 | PMID: 30612599
Tóm tắt Chức năng
Vitamin D3 activates the autolysosomal degradation function against Helicobacter pylori through the PDIA3 receptor in gastric epithelial cells.
Hu W, Zhang L, Li MX, Shen J, Liu XD, Xiao ZG, Wu DL, Ho IHT, Wu JCY, Cheung CKY, Zhang YC, Lau AHY, Ashktorab H, Smoot DT, Fang EF, Chan MTV, Gin T, Gong W, Wu WKK, Cho CH.
Autophagy. 2019 Jan 6;:1-19 | doi: 10.1080/15548627.2018.1557835 | PMID: 30612517
Tóm tắt Chức năng
Epigenetic changes around the pX region and spontaneous HTLV-1 transcription are CTCF-independent.
Miura M, Miyazato P, Satou Y, Tanaka Y, Bangham CRM.
Wellcome open research. 2018;3:105 | doi: 10.12688/wellcomeopenres.14741.2 | PMID: 30607369 | PMC: PMC6305241
Tóm tắt Chức năng
Generation of gene-corrected human induced pluripotent stem cell lines derived from retinitis pigmentosa patient with Ser331Cysfs*5 mutation in MERTK.
Artero Castro A, Long K, Bassett A, Machuca C, León M, Ávila-Fernandez A, Cortón M, Vidal-Puig T, Ayuso C, Lukovic D, Erceg S.
Stem cell research. 2018 Nov 16;34:101341 | doi: 10.1016/j.scr.2018.11.003 | PMID: 30612079
Tóm tắt Chức năng
CRISPR/Cas9-mediated gene editing in an exogenous transgene and an endogenous sex determination gene in the Caribbean fruit fly, Anastrepha suspensa.
Li J, Handler AM.
Gene. 2019 Jan 3;691:160-166 | doi: 10.1016/j.gene.2018.12.055 | PMID: 30611840
Tóm tắt Chức năng
Identification of a novel function of the silkworm integument in nitrogen metabolism: Uric acid is synthesized within the epidermal cells in B. mori.
Fujii T, Banno Y.
Insect biochemistry and molecular biology. 2019 Jan 2;105:43-50 | doi: 10.1016/j.ibmb.2018.12.014 | PMID: 30610924
Tóm tắt Chức năng
DNA-Free Genome Editing via Ribonucleoprotein (RNP) Delivery of CRISPR/Cas in Lettuce.
Park J, Choi S, Park S, Yoon J, Park AY, Choe S.
Methods in molecular biology (Clifton, N.J.). 2019;1917:337-354 | doi: 10.1007/978-1-4939-8991-1_25 | PMID: 30610648
Tóm tắt Chức năng
Biolistic Delivery of CRISPR/Cas9 with Ribonucleoprotein Complex in Wheat.
Liang Z, Chen K, Gao C.
Methods in molecular biology (Clifton, N.J.). 2019;1917:327-335 | doi: 10.1007/978-1-4939-8991-1_24 | PMID: 30610647
Tóm tắt Chức năng
Virus-Mediated Genome Editing in Plants Using the CRISPR/Cas9 System.
Mahas A, Ali Z, Tashkandi M, Mahfouz MM.
Methods in molecular biology (Clifton, N.J.). 2019;1917:311-326 | doi: 10.1007/978-1-4939-8991-1_23 | PMID: 30610646
Tóm tắt Chức năng
Targeted Base Editing with CRISPR-Deaminase in Tomato.
Shimatani Z, Ariizumi T, Fujikura U, Kondo A, Ezura H, Nishida K.
Methods in molecular biology (Clifton, N.J.). 2019;1917:297-307 | doi: 10.1007/978-1-4939-8991-1_22 | PMID: 30610645
Tóm tắt Chức năng
Gene Replacement by Intron Targeting with CRISPR-Cas9.
Li J, Meng X, Li J, Gao C.
Methods in molecular biology (Clifton, N.J.). 2019;1917:285-296 | doi: 10.1007/978-1-4939-8991-1_21 | PMID: 30610644
Tóm tắt Chức năng
Targeted Mutagenesis Using FnCpf1 in Tobacco.
Endo A, Toki S.
Methods in molecular biology (Clifton, N.J.). 2019;1917:269-281 | doi: 10.1007/978-1-4939-8991-1_20 | PMID: 30610643
Tóm tắt Chức năng
Editing a Stomatal Developmental Gene in Rice with CRISPR/Cpf1.
Yin X, Anand A, Quick P, Bandyopadhyay A.
Methods in molecular biology (Clifton, N.J.). 2019;1917:257-268 | doi: 10.1007/978-1-4939-8991-1_19 | PMID: 30610642
Tóm tắt Chức năng
Plant Gene Knockout and Knockdown by CRISPR-Cpf1 (Cas12a) Systems.
Zhang Y, Zhang Y, Qi Y.
Methods in molecular biology (Clifton, N.J.). 2019;1917:245-256 | doi: 10.1007/978-1-4939-8991-1_18 | PMID: 30610641
Tóm tắt Chức năng
Genome Editing in Citrus Tree with CRISPR/Cas9.
Jia H, Zou X, Orbovic V, Wang N.
Methods in molecular biology (Clifton, N.J.). 2019;1917:235-241 | doi: 10.1007/978-1-4939-8991-1_17 | PMID: 30610640
Tóm tắt Chức năng
Genome Editing in Soybean with CRISPR/Cas9.
Liu J, Gunapati S, Mihelich NT, Stec AO, Michno JM, Stupar RM.
Methods in molecular biology (Clifton, N.J.). 2019;1917:217-234 | doi: 10.1007/978-1-4939-8991-1_16 | PMID: 30610639
Tóm tắt Chức năng
Visual Assay for Gene Editing Using a CRISPR/Cas9 System in Carrot Cells.
Klimek-Chodacka M, Oleszkiewicz T, Baranski R.
Methods in molecular biology (Clifton, N.J.). 2019;1917:203-215 | doi: 10.1007/978-1-4939-8991-1_15 | PMID: 30610638
Tóm tắt Chức năng
Genome Editing in Potato with CRISPR/Cas9.
Nadakuduti SS, Starker CG, Voytas DF, Buell CR, Douches DS.
Methods in molecular biology (Clifton, N.J.). 2019;1917:183-201 | doi: 10.1007/978-1-4939-8991-1_14 | PMID: 30610637
Tóm tắt Chức năng
Application of CRISPR/Cas9-Mediated Gene Editing in Tomato.
Reem NT, Van Eck J.
Methods in molecular biology (Clifton, N.J.). 2019;1917:171-182 | doi: 10.1007/978-1-4939-8991-1_13 | PMID: 30610636
Tóm tắt Chức năng
Creating Targeted Gene Knockouts in Brassica oleracea Using CRISPR/Cas9.
Lawrenson T, Hundleby P, Harwood W.
Methods in molecular biology (Clifton, N.J.). 2019;1917:155-170 | doi: 10.1007/978-1-4939-8991-1_12 | PMID: 30610635
Tóm tắt Chức năng
Fluorescence Marker-Assisted Isolation of Cas9-Free and CRISPR-Edited Arabidopsis Plants.
Yu H, Zhao Y.
Methods in molecular biology (Clifton, N.J.). 2019;1917:147-154 | doi: 10.1007/978-1-4939-8991-1_11 | PMID: 30610634
Tóm tắt Chức năng
An Agrobacterium-Mediated CRISPR/Cas9 Platform for Genome Editing in Maize.
Lee K, Zhu H, Yang B, Wang K.
Methods in molecular biology (Clifton, N.J.). 2019;1917:121-143 | doi: 10.1007/978-1-4939-8991-1_10 | PMID: 30610633
Tóm tắt Chức năng
Knocking Out MicroRNA Genes in Rice with CRISPR-Cas9.
Zhou J, Zhong Z, Chen H, Li Q, Zheng X, Qi Y, Zhang Y.
Methods in molecular biology (Clifton, N.J.). 2019;1917:109-119 | doi: 10.1007/978-1-4939-8991-1_9 | PMID: 30610632
Tóm tắt Chức năng
Generating Photoperiod-Sensitive Genic Male Sterile Rice Lines with CRISPR/Cas9.
Gu W, Zhang D, Qi Y, Yuan Z.
Methods in molecular biology (Clifton, N.J.). 2019;1917:97-107 | doi: 10.1007/978-1-4939-8991-1_8 | PMID: 30610631
Tóm tắt Chức năng
CRISPR-Act2.0: An Improved Multiplexed System for Plant Transcriptional Activation.
Malzahn A, Zhang Y, Qi Y.
Methods in molecular biology (Clifton, N.J.). 2019;1917:83-93 | doi: 10.1007/978-1-4939-8991-1_7 | PMID: 30610630
Tóm tắt Chức năng
A Single Transcript CRISPR-Cas9 System for Multiplex Genome Editing in Plants.
Tang X, Zhong Z, Ren Q, Liu B, Zhang Y.
Methods in molecular biology (Clifton, N.J.). 2019;1917:75-82 | doi: 10.1007/978-1-4939-8991-1_6 | PMID: 30610629
Tóm tắt Chức năng
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